At Any Age, It Does Matter:
Substance Abuse and Older Adults
(for Professionals)
Module 5: Recognizing Other Forms of Substance Abuse
- Page 9
of 31
Drug-Alcohol Interactions
Any use of drugs and alcohol carries risk, abuse of these substances raises the risk, and multiple drug use further increases the risk. A recent study documented the many possible unfavorable reactions between medications and alcohol.50 For example:
- Chronic alcoholics who use even therapeutic doses of acetaminophen (e.g., Tylenol) may experience liver damage. A recent study found that the combination of alcohol and over-the-counter pain medications was the most common source of adverse drug reactions among older patients.51
- Alcohol can increase lithium toxicity and enhance central nervous system depression in persons taking tricyclic antidepressants (e.g., Elavil, Wellbutrin).
- High doses of benzodiazepines (e.g., Valium, Ativan, Halcion) used in conjunction with alcohol or barbiturates can be lethal.41
Such interactions can result from a lack of understanding about the potential dangers of consuming alcohol when taking certain medications.








